Combining Cyclobenzaprine and Ibuprofen: Is It Worth It?

This page will go over its side effects, drug interactions, and treatment for misuse. Flexeril and Diazepam are both used to treat muscle spasms. They belong to two different drug classes – muscle relaxant and benzodiazepine, respectively. The only salient difference is that Valium has a higher potential to cause drug dependency than Flexeril.

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Another rare side effect is an allergic reaction to the drug, manifested by hives and trouble breathing. Most insurance and Medicare Part D plans cover Flexeril (generic). A typical prescription of generic Flexeril would cost about $20 out-of-pocket, but with SingleCare you can purchase the generic Flexeril for about $7-$8 at participating pharmacies.

What If We Consume Flexeril And Ibuprofen Together?

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor. Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study.

In one study published in the British Medical Journal, Valium increases the effects of spasmolytic agents. When combined, these drugs can increase the severity of CNS side effects. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Data sources include IBM Watson Micromedex (updated 3 Sep 2023), Cerner Multum™ (updated 28 Aug 2023), ASHP (updated 10 Aug 2023) and others. Flexeril (cyclobenzaprine) is a muscle relaxant that is used for short-term (2-3 weeks) treatment of muscle spasms along with rest and physical therapy.

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The way they work is not completely understood, but may be due to central nervous system (CNS) depression and sedative effects. These medications do not act directly on the muscle or nerves. Mixing cocaine and muscle relaxants come with dangerous interactions and side effects.

Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. Because of the possibility of higher blood levels in the elderly as compared to younger adults, use of cyclobenzaprine extended-release capsules is not recommended in the elderly. Appropriate studies have not been performed on the relationship of age to the effects of cyclobenzaprine extended-release capsules in the pediatric population.

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As both medications are relatively short-acting (~4-12 hours per dose), they could potentially be dosed on the same day, just not at the same time. While the addictiveness of cyclobenzaprine is being debated, anyone exhibiting problematic patterns of substance flexeril sleep aid use can benefit from addiction treatment. This is especially true if someone has been engaging in polydrug use with cyclobenzaprine and other substances. It blocks the pathways of neurotransmitters that signal pain and diminishes the sensations of pain.

• Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).
• Drowsiness, dizziness, dry mouth, constipation, or tiredness may occur.
• If use together is necessary, it is prudent to use the lowest dose and shortest duration necessary to achieve treatment goals.
• Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) widely used to alleviate pain, reduce inflammation, and lower fever.
• In these cases, your doctor may want to change the dose, or other precautions may be necessary.

Just remember to talk to your physician before you stop the current prescription and move on to a different treatment plan. For one, a randomized trial proved that cyclobenzaprine alone calms neck and back spasms just as well as a cyclobenzaprine-ibuprofen combination. Sign in to your account to save this drug interaction list. USE WITH CAUTIONAspirin (For certain people – see below) Used to prevent heart attacks and strokes.

Check Interactions

After all, the muscle relaxant is supposed to be taken short-term only. So, it’s not unheard of for an orthopedic doctor to co-prescribe both drugs in an attempt to give the patient short-term pain relief. Before mixing OTC painkillers with muscle relaxants, you need to evaluate whether this combination yields better results with fewer side effects than a single drug. However, this does not necessarily mean no interactions exist.

For temporary relief, use sugarless candy or gum, melt bits of ice in your mouth, or use a saliva substitute. However, if your mouth continues to feel dry for more than 2 weeks, check with your medical doctor or dentist. Continuing dryness of the mouth may increase the chance of dental disease, including tooth decay, gum disease, and fungus infections. JAMA Network Open found that the misuse of muscle relaxants, including cyclobenzaprine, increased significantly during this period. Both cyclobenzaprine and ibuprofen are widely recognized medications that can relieve different types of pain, but they function in distinct ways and target different aspects of discomfort. If someone is trying to find out whether one can take these drugs and ibuprofen together, it is not recommended to mix both of them.